Transcriptional regulation via TF-modifying enzymes: an integrative model-based analysis
نویسندگان
چکیده
منابع مشابه
Transcriptional regulation via TF-modifying enzymes: an integrative model-based analysis
Transcription factor activity is largely regulated through post-translational modification. Here, we report the first integrative model of transcription that includes both interactions between transcription factors and promoters, and between transcription factors and modifying enzymes. Simulations indicate that our method is robust against noise. We validated our tool on a well-studied stress r...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2011
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkr172